Helps Solidify Biophysics Applications of Lasers
Dr. Clarence Capjack and Dr. Wojciech Rozmus of the
University of Alberta, studying matter under extreme
conditions has taken on a new dimension. Their
current research project is crossing over from traditional
theoretical challenges of plasma and laser physics to
an applied research approach where they are using numerical
codes to develop and design a powerful diagnostic tool.
the support of the MACI computational grid of resources,
Capjack and Rozmus and members of their group, Dr. A.
Maximov (research associate) and Yunfeng Shao (graduate
student) have developed new numerical algorithms, based
on a spectral method that analyzes the scattering of
electromagnetic radiation from biological cells. Their
numerical algorithm, computationally, is proving to
be very successful. The model includes a nonparaxial
electromagnetic wave equation, where cells are described
in terms of perturbations of an index of refraction.
With the breakthrough of this theoretical approach Capjack
and Rozmus have teamed up with Dr. Chris Backhouse from
the Department of Electrical and Computer Engineering
in an effort to design and build a new biomedical diagnostic
tool, called a microcytometer.
new three parameter microcytometer is a powerful version
of the biomedical tool which has extensive capabilities
to analyze cells. Their design will allow for the easy
identification of cell size, as well as internal structure
and chemical composition. The implications of this design
are great. Not only will this microcytometer enable
the consistent analysis of cells, it also has the potential
to greatly influence the biomedical field with respect
to the future of tissue analysis and exploration.
MACI infrastructure at the University of Alberta has
played an integral part in this research duos
success. The development and design of Rozmus
and Capjacks computationally intensive algorithm
would not have been possible with out the immense storage
and memory capabilities of a high performance computer
system. Continued technological support of this extent
are essential, to ensure the continuation of leading
edge biomedical research and success.
Shao, A. Maximov, I. Ourdev, W. Rozmus and C. E. Capjack.
Spectral Method Simulations of Light Scattering by
Biological Cells, IEEE Journal of Quantum Electronics,
in press, 2001.
Maximov, I. Ourdev, D. Pesme, W. Rozmus, V.T. Tikhonchuk
and C.E. Capjack. Plasma Induced Smoothing of a Spatially
Incoherent Laser Beam and Reduction of Backward Stimulates
Brillouin Scattering, Phys. Plasmas, 8
in press, 2001.
Fourkal, V. Yu Bychenkov, W. Rozmus, R. Sydora, C. Kikrby,
C. E. Capjack, S Glenzer, H. Baldis. Electron Distribution
Function in Laser Heated Plasmas, Phys. Plasmas,
8, 550-556, 2001.
Pesme, W. Rozmus, V. T. Tikhonchuk, A. Maximov, I.
Ourdev, C. H. Still. Resonant Instability of Laser
Filaments in a Plasma, Phys. Rev. Lett.,
84 278-282, 2000.
Labaune, H. Baldis, E. Schiffano, B. Bauer, A. Maximov,
I. Ourdev, W. Rozmus and D. Pesme. Enhanced Forward
Scattering in the Case of Two Crossed Laser beams Interacting
with a Plasma, Phys. Rev. Lett., 85
Maximov, R. Oppitz, W. Rozmus, V. Tikhonchuk, Nonlinear
Stimulated Brillouin Scattering in Inhomogeneous Plasmas,
Phys. Plasmas, 7, 4227-4237,